ISI JRF in Human Genetics Sample Model Papers 2020
Indian Statistical Institute ISI JRF in Human Genetics 2020 Model Question Papers 2020 ISI JRF in Human Genetics Sample Question papers ISI JRF in Human Genetics Mock Test Question Paper for 2020 Exam, This ISI JRF in Human Genetics Question are based on the syllabus but here some of the question may out of syllabus, just for your better exam ISI JRF in Human Genetics Exam preparation.
ISI JRF in Human Genetics Sample Model Papers 2020.
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Phenylketonuria (PKU) is a rare autosomal recessive disease. A couple who are both normal decide to have children. The man has a brother with PKU and the woman has a sister with PKU. There are no other known cases in the family.
a) Deduce the genotypes of the man’s brother and woman’s sister.
b) What are the genotypes of the man and woman’s parents?
c) What is the probability that the couple’s first child will have PKU?
1. In crosses of the fruit-fly Drosophila, Thomas Hunt Morgan collected data on 2839 flies pertaining to two autosomal loci. The first locus has two alleles denoted as A and a, while the second locus has two alleles denoted as B and b. The 2839 flies were all progeny of the following mating: AaBb x aabb. The observed frequencies of genotypes of the flies were: AaBb=1339, Aabb=151, aaBb=154 and aabb=1195. Provide a genetic model for these data (the relative locations of the two loci on chromosomes and an explanation for the observed genotype frequencies).
2. Explain Lambert- Beers Law. Why does the absorbance of equimolar amounts of tryptophan and tyrosine differ, at 280 nm? Explain why mutation of a protein can lead to change in absorbance at 280nm?